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BAFF controls B cell metabolic fitness through a PKCβ- and Akt-dependent mechanism
B cell life depends critically on the cytokine B cell–activating factor of the tumor necrosis factor family (BAFF). Lack of BAFF signaling leads to B cell death and immunodeficiency. Excessive BAFF signaling promotes lupus-like autoimmunity. Despite the great importance of BAFF to B cell biology, it...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118121/ https://ncbi.nlm.nih.gov/pubmed/17060474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060990 |
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