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Chewing the fat on natural killer T cell development

Natural killer T cells (NKT cells) are selected in the thymus by self-glycolipid antigens presented by CD1d molecules. It is currently thought that one specific component of the lysosomal processing pathway, which leads to the production of isoglobotrihexosylceramide (iGb3), is essential for normal...

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Bibliographic Details
Main Authors: Godfrey, Dale I., McConville, Malcolm J., Pellicci, Daniel G.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118098/
https://ncbi.nlm.nih.gov/pubmed/17000869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061787
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