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Paraoxonase promoter and intronic variants modify risk of sporadic amyotrophic lateral sclerosis
BACKGROUND: The paraoxonases, PON1–3, play a major protective role both against environmental toxins and as part of the antioxidant defence system. Recently, non‐synonymous coding single nucleotide polymorphisms (SNPs), known to lower serum PON activity, have been associated with sporadic ALS (SALS)...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2117866/ https://ncbi.nlm.nih.gov/pubmed/17702780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.2006.112581 |
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