Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells

The proprotein convertases (PCs) are implicated in the activation of various precursor proteins that play an important role in tumor cell metastasis. Here, we report their involvement in the regulation of the metastatic potential of colorectal tumor cells. PC function in the human and murine colon c...

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Detaylı Bibliyografya
Asıl Yazarlar: Scamuffa, Nathalie, Siegfried, Geraldine, Bontemps, Yannick, Ma, Liming, Basak, Ajoy, Cherel, Ghislaine, Calvo, Fabien, Seidah, Nabil G., Khatib, Abdel-Majid
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2007
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2117762/
https://ncbi.nlm.nih.gov/pubmed/18064302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32040
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