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Experimental transmission of scrapie agent to susceptible sheep by intralingual or intracerebral inoculation

Scrapie, a transmissible spongiform encephalopathy (TSE), is a naturally occurring fatal neurodegenerative disease of sheep and goats. This study documents survival periods, pathological findings, and the presence of abnormal prion protein (PrP(Sc)) in genetically susceptible sheep inoculated with s...

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Auteurs principaux: Hamir, Amir N., Kunkle, Robert A., Bulgin, Marie S., Rohwer, Robert G., Gregori, Luisa, Richt, Juergen A.
Format: Artigo
Langue:Inglês
Publié: Canadian Veterinary Medical Association 2008
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2117369/
https://ncbi.nlm.nih.gov/pubmed/18214164
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