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Alpha‐1‐antitrypsin deficiency: optimal therapeutic regimen based on population pharmacokinetics
BACKGROUND: Exogenous doses of 60 mg/kg α(1)‐antitrypsin (AAT) every 7 days are recommended in patients with severe AAT deficiency. However, long term administration of weekly doses is not well accepted by patients. Using pharmacokinetic simulations, we evaluated whether steady state minimum concent...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Group
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2117047/ https://ncbi.nlm.nih.gov/pubmed/16928711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2005.057943 |
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