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NH2-terminal substitutions of basic amino acids induce translocation across the microsomal membrane and glycosylation of rabbit cytochrome P450IIC2

Insertion of rabbit cytochrome P450IIC2 and its modified form, [2-lys,3- arg]P450IIC2, into microsomal membranes was studied in an in vitro transcription/translation/translocation system. Cytochrome P450IIC2, synthesized in the presence of chicken oviduct microsomal membranes, was resistant to extra...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1989
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2115505/
https://ncbi.nlm.nih.gov/pubmed/2494191
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