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Two independent mechanisms for escaping epidermal growth factor- mediated growth inhibition in epidermal growth factor receptor- hyperproducing human tumor cells

Human squamous cell carcinoma cell lines often possess increased levels of epidermal growth factor (EGF) receptor. The growth of these EGF receptor-hyperproducing cells is usually inhibited by EGF. To investigate the mechanism of EGF-mediated inhibition of cell growth, variants displaying alternate...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1988
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2115197/
https://ncbi.nlm.nih.gov/pubmed/2458359
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