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Mitogen-activated protein kinases enhance long-range activation by the β-globin locus control region

The human β-globin locus control region (LCR), which consists of four erythroid-specific DNase I hypersensitive sites (HS1–HS4), functions over a long distance to control the transcription, chromatin structure, and replication of the β-globin genes. We have used stable transfection assays to show th...

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Autori principali: Versaw, Wayne K., Blank, Volker, Andrews, Nancy M., Bresnick, Emery H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC21149/
https://ncbi.nlm.nih.gov/pubmed/9671751
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