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Lowering pH in blood platelets dissociates myosin phosphorylation from shape change and myosin association with the cytoskeleton

Platelet shape change induced by ADP is relatively independent of external pH over the range 6-7. If the chloride ion in the buffer is replaced by weak acids, however, shape change is rapidly and reversibly inhibited as a function of lowered pH (92% at pH 6.0). This inhibition is correlated with low...

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Detalhes bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1987
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2114642/
https://ncbi.nlm.nih.gov/pubmed/3667696
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