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Chinese hamster ovary cell mutants with temperature-sensitive defects in endocytosis. I. Loss of function on shifting to the nonpermissive temperature

We have isolated three independent Chinese hamster ovary cell mutants (B3853, I223, and M311) with temperature-sensitive, pleiotropic defects in receptor-mediated endocytosis. Activities affected at 41 degrees C include uptake via the D-mannose 6-phosphate receptor, accumulation of Fe from diferric...

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Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1986
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2114594/
https://ncbi.nlm.nih.gov/pubmed/2946705
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