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Temperature-Sensitive Chinese Hamster Fibroblast Mutant with a Defect in RNA Metabolism

We describe a new temperature-sensitive mutant of Chinese hamster cell fibroblasts. After a shift to the nonpermissive temperature of 40.5°C, the rates of DNA, RNA, and protein synthesis declined rapidly (to ≤50% within 12 h) and the progression of unsynchronized cells through the cell cycle was aff...

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Detalhes bibliográficos
Main Authors: Wong, Eric A., Scheffler, Immo E.
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC369964/
https://ncbi.nlm.nih.gov/pubmed/14582197
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