Bloom’s and Werner’s syndrome genes suppress hyperrecombination in yeast sgs1 mutant: Implication for genomic instability in human diseases

Bloom’s syndrome (BS) and Werner’s syndrome (WS) are genetic disorders in which an increased rate of chromosomal aberration is detected. The genes responsible for these diseases, BLM and WRN, have been found to be homologs of Escherichia coli recQ and Saccharomyces cerevisiae SGS1 genes. Here we sho...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Yamagata, Kazutsune, Kato, Jun-ichi, Shimamoto, Akira, Goto, Makoto, Furuichi, Yasuhiro, Ikeda, Hideo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences 1998
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC21145/
https://ncbi.nlm.nih.gov/pubmed/9671747
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