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Exposure of K562 cells to anti-receptor monoclonal antibody OKT9 results in rapid redistribution and enhanced degradation of the transferrin receptor

When the human erythroleukemia cell line K562 is treated with OKT9, a monoclonal antibody against the transferrin receptor, effects on receptor dynamics and degradation ensue. The apparent half-life of the receptor is decreased by greater than 50% as a result of OKT9 treatment. The transferrin recep...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1986
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2114135/
https://ncbi.nlm.nih.gov/pubmed/3005341
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