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Nerve growth factor-induced neurite outgrowth in PC12 cells involves the coordinate induction of microtubule assembly and assembly-promoting factors

Nerve growth factor (NGF) regulates the microtubule-dependent extension and maintenance of axons by some peripheral neurons. We show here that one effect of NGF is to promote microtubule assembly during neurite outgrowth in PC12 cells. Though NGF causes an increase in total tubulin levels, the forma...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1985
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2113947/
https://ncbi.nlm.nih.gov/pubmed/2997236
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