Cloning and expression in Escherichia coli of isopenicillin N synthetase genes from Streptomyces lipmanii and Aspergillus nidulans.

beta-Lactam antibiotics such as penicillins and cephalosporins are synthesized by a wide variety of microbes, including procaryotes and eucaryotes. Isopenicillin N synthetase catalyzes a key reaction in the biosynthetic pathway of penicillins and cephalosporins. The genes encoding this protein have...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Weigel, B J, Burgett, S G, Chen, V J, Skatrud, P L, Frolik, C A, Queener, S W, Ingolia, T D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC211376/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3045077/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.170.9.3817-3826.1988
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