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Rapid rate of tubulin dissociation from microtubules in the mitotic spindle in vivo measured by blocking polymerization with colchicine
At metaphase, the amount of tubulin assembled into spindle microtubules is relatively constant; the rate of tubulin association equals the rate of dissociation. To measure the intrinsic rate of dissociation, we microinjected high concentrations of colchicine, or its derivative colcemid, into sea urc...
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| Format: | Artigo |
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| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
1984
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2113402/ https://ncbi.nlm.nih.gov/pubmed/6470037 |
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