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Motif module map reveals enforcement of aging by continual NF-κB activity
Aging is characterized by specific alterations in gene expression, but their underlying mechanisms and functional consequences are not well understood. Here we develop a systematic approach to identify combinatorial cis-regulatory motifs that drive age-dependent gene expression across different tiss...
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Principais autores: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2113026/ https://ncbi.nlm.nih.gov/pubmed/18055696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1588507 |
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