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Epidermal growth factor and thyrotropin-releasing hormone act similarly on a clonal pituitary cell strain. Modulation of hormone production and inhibition of cell proliferation

GH(4)C(1) cells are a clonal strain of rat pituitary cells that synthesize and secrete prolactin and growth hormone. Chronic treatment (longer than 24 h) of GH(4)C(1) cells with epidermal growth factor (EGF) (10(-8) M) decreased by 30-40 percent both the rate of cell proliferation and the plateau de...

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Detalhes bibliográficos
Main Authors: Schonbrunn, A, Krasnoff M, Westendorf J, Tashjian, A
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2111439/
https://ncbi.nlm.nih.gov/pubmed/6771298
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