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The interaction of benzodiazepines with thyrotropin-releasing hormone receptors on clonal pituitary cells.

1. Seven benzodiazepines were investigated for their ability to interact with receptors for thyrotropin-releasing hormone (TRH) on GH3 and GH4C1 pituitary tumour cells. 2. Midazolam and chlordiazepoxide were the most potent inhibitors of TRH-induced [3H]-inositol phosphate formation with Ki values i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Joels, L. A., Drummond, A. H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1989
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854371/
https://ncbi.nlm.nih.gov/pubmed/2538195
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