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Polyunsaturated Fatty Acids Induce α-Synuclein-Related Pathogenic Changes in Neuronal Cells

The misfolding and aggregation of normally soluble proteins has emerged as a key feature of several neurodegenerative diseases. In Parkinson’s disease, progressive loss of dopaminergic neurons is accompanied by polymerization of the cytoplasmic protein α-synuclein (αS) into filamentous inclusions fo...

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Bibliografiske detaljer
Main Authors: Assayag, Karen, Yakunin, Evgenia, Loeb, Virginie, Selkoe, Dennis J., Sharon, Ronit
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2111122/
https://ncbi.nlm.nih.gov/pubmed/18055555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070373
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