Homeostatic Control of the Crypt-Villus Axis by the Bacterial Enterotoxin Receptor Guanylyl Cyclase C Restricts the Proliferating Compartment in Intestine

Guanylyl cyclase C (GC-C), the receptor for diarrheagenic enterotoxins and the paracrine ligands guanylin and uroguanylin, regulates intestinal secretion. Beyond volume homeostasis, its importance in modulating cancer cell proliferation and its uniform dysregulation early in colon carcinogenesis, re...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Li, Peng, Lin, Jieru E., Chervoneva, Inna, Schulz, Stephanie, Waldman, Scott A., Pitari, Giovanni M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2007
Предметы:
Regular Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2111108/
https://ncbi.nlm.nih.gov/pubmed/17974601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070198
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы