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Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways

A multiprotein complex isolated from murine cells is identified as a counterpart of the yeast Mediator of transcriptional regulation on the basis of the following: homologs of two subunits of yeast Mediator, Srb7 and Med7, copurify with the complex; peptide sequencing reveals, in addition, homologs...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Jiang, Yi Wei, Veschambre, Philippe, Erdjument-Bromage, Hediye, Tempst, Paul, Conaway, Joan W., Conaway, Ronald C., Kornberg, Roger D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21111/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9671713/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.15.8538
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