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Analysis of lipopolysaccharide biosynthesis in Salmonella typhimurium and Escherichia coli by using agents which specifically block incorporation of 3-deoxy-D-manno-octulosonate.

Antibacterial agents which specifically inhibit CTP:CMP-3-deoxy-D-manno-octulosonate cytidylyltransferase activity were used to block the incorporation of 3-deoxy-D-manno-octulosonate (KDO) into lipopolysaccharide. Lipopolysaccharide synthesis ceased, molecules similar in structure to lipid A accumu...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Bacteriol
Principais autores: Goldman, R C, Doran, C C, Capobianco, J O
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 1988
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC211104/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2834331/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.170.5.2185-2191.1988
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