Analysis of lipopolysaccharide biosynthesis in Salmonella typhimurium and Escherichia coli by using agents which specifically block incorporation of 3-deoxy-D-manno-octulosonate.

Antibacterial agents which specifically inhibit CTP:CMP-3-deoxy-D-manno-octulosonate cytidylyltransferase activity were used to block the incorporation of 3-deoxy-D-manno-octulosonate (KDO) into lipopolysaccharide. Lipopolysaccharide synthesis ceased, molecules similar in structure to lipid A accumu...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Goldman, R C, Doran, C C, Capobianco, J O
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1988
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC211104/
https://ncbi.nlm.nih.gov/pubmed/2834331
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