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125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts

125I-labeled human epidermal growth factor (hEGF) binds in a specific and saturable manner to human fibroblasts. At 37 degrees C, the cell- bound 125I-hEGF initially may be recovered in a native form by acid extraction; upon subsequent incubation, the cell-bound 125I-hEGF is degraded very rapidly, w...

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Bibliografski detalji
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1976
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2109737/
https://ncbi.nlm.nih.gov/pubmed/977646
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