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THE ACTION OF α-AMANITIN ON RNA SYNTHESIS IN CHINESE HAMSTER OVARY CELLS : Ultrastructural and Biochemical Studies

α-Amanitin acts in vitro as a selective inhibitor of the nucleoplasmic form B RNA polymerases. Treatment of Chinese hamster ovary (CHO) cells with this drug leads principally to a severe fragmentation of the nucleoli. While the ultrastructural lesions induced by α-amanitin in CHO cells and in rat or...

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Bibliografiske detaljer
Main Authors: Kedinger, Claude, Simard, Rene
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1974
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2109362/
https://ncbi.nlm.nih.gov/pubmed/4474178
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