INFLUENCE OF THE MUTATION "DIABETES" ON INSULIN RELEASE AND ISLET MORPHOLOGY IN MICE OF DIFFERENT GENETIC BACKGROUNDS

Mice, 7–8-mo old, of the C57BL/KsJ-db strain and homozygotic for the mutant gene db, exhibited marked hyperglycemia and moderately elevated serum insulin levels. Light and electron microscopy provided evidence of a slightly decreased proportion of β cells in the pancreatic islets, irregular islet ar...

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Main Authors: Boquist, L., Hellman, B., Lernmark, Å., Täljedal, I.-B.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1974
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2109181/
https://ncbi.nlm.nih.gov/pubmed/4135113
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