DNA gyrase gyrA mutations in ciprofloxacin-resistant strains of Staphylococcus aureus: close similarity with quinolone resistance mutations in Escherichia coli.

The gyrA genes isolated from three ciprofloxacin-resistant clinical isolates of Staphylococcus aureus carried codon 84 (serine----leucine) and/or codon 85 (serine----proline) mutations that were absent in pretreatment susceptible strains. These substitutions occur in a region of the gyrase A protein...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Sreedharan, S, Oram, M, Jensen, B, Peterson, L R, Fisher, L M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC210851/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2174869/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.172.12.7260-7262.1990
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