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THE EFFECT OF ETHIDIUM BROMIDE ON MITOCHONDRIAL DNA SYNTHESIS AND MITOCHONDRIAL DNA STRUCTURE IN HELA CELLS
The synthesis of mitochondrial DNA (mDNA) in HeLa cells is selectively inhibited by relatively low concentrations of ethidium bromide. After exposure of cells to strongly inhibitory concentrations of the drug, the apparent superhelix density of mDNA is rapidly increased, as judged by its buoyant den...
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| Natura: | Artigo |
| Lingua: | Inglês |
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The Rockefeller University Press
1971
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2108249/ https://ncbi.nlm.nih.gov/pubmed/5111872 |
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