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THE MECHANISM OF ACTION OF COLCHICINE : Colchicine Binding to Sea Urchin Eggs and the Mitotic Apparatus

Colchicine forms a complex in vivo with a protein present in fertilized or unfertilized sea urchin eggs; similar binding was obtained in vitro with the soluble fraction from egg homogenates. Kinetic parameters and binding equilibrium constant were essentially the same in vivo and in vitro. The bindi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Borisy, G. G., Taylor, E. W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1967
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2107308/
https://ncbi.nlm.nih.gov/pubmed/6035643
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