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THE MECHANISM OF ACTION OF COLCHICINE : Colchicine Binding to Sea Urchin Eggs and the Mitotic Apparatus

Colchicine forms a complex in vivo with a protein present in fertilized or unfertilized sea urchin eggs; similar binding was obtained in vitro with the soluble fraction from egg homogenates. Kinetic parameters and binding equilibrium constant were essentially the same in vivo and in vitro. The bindi...

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Détails bibliographiques
Auteurs principaux: Borisy, G. G., Taylor, E. W.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1967
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2107308/
https://ncbi.nlm.nih.gov/pubmed/6035643
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