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THE MECHANISM OF COLCHICINE INHIBITION OF MITOSIS : I. Kinetics of Inhibition and the Binding of H(3)-Colchicine
H(3)-colchicine of high specific activity (2.5 curies per mM) was prepared in order to study the mechanism of colchicine inhibition of mitosis in cultures of human cells, strain K.B. No direct effects on the duration of the cell cycle or macromolecular synthesis were demonstrable at a concentration...
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| Format: | Artigo |
| Jezik: | Inglês |
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The Rockefeller University Press
1965
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2106604/ https://ncbi.nlm.nih.gov/pubmed/14342828 |
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