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Ubiquitin-mediated signalling and Paget's disease of bone
Multiple steps in the RANK-NF-κB signalling pathway are regulated by ubiquitylation. Mutations affecting different components of this pathway, including the ubiquitin binding p62 signalling adapter protein, are found in patients with Paget's disease of bone or related syndromes. Here, we review...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2106369/ https://ncbi.nlm.nih.gov/pubmed/18047742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-8-S1-S5 |
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