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Ubiquitin-mediated signalling and Paget's disease of bone

Multiple steps in the RANK-NF-κB signalling pathway are regulated by ubiquitylation. Mutations affecting different components of this pathway, including the ubiquitin binding p62 signalling adapter protein, are found in patients with Paget's disease of bone or related syndromes. Here, we review...

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Detalhes bibliográficos
Main Authors: Layfield, Robert, Shaw, Barry
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2106369/
https://ncbi.nlm.nih.gov/pubmed/18047742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-8-S1-S5
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