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Ubiquitin-mediated signalling and Paget's disease of bone

Multiple steps in the RANK-NF-κB signalling pathway are regulated by ubiquitylation. Mutations affecting different components of this pathway, including the ubiquitin binding p62 signalling adapter protein, are found in patients with Paget's disease of bone or related syndromes. Here, we review...

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Bibliografiske detaljer
Main Authors: Layfield, Robert, Shaw, Barry
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2106369/
https://ncbi.nlm.nih.gov/pubmed/18047742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-8-S1-S5
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