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Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation

We have studied mechanisms by which leptin overexpression, which reduces body weight via anorexic and thermogenic actions, induces triglyceride depletion in adipocytes and nonadipocytes. Here we show that leptin alters in pancreatic islets the mRNA of the genes encoding enzymes of free fatty acid me...

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Autors principals: Zhou, Yan-Ting, Shimabukuro, Michio, Koyama, Kazunori, Lee, Young, Wang, May-Yun, Trieu, Falguni, Newgard, Christopher B., Unger, Roger H.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC21059/
https://ncbi.nlm.nih.gov/pubmed/9177227
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