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Enhanced upregulation of smooth muscle related transcripts by TGFβ(2) in asthmatic (myo) fibroblasts

BACKGROUND: Transforming growth factor beta (TGFβ) upregulates a number of smooth muscle specific genes in (myo)fibroblasts. As asthma is characterised by an increase in airway smooth muscle, we postulated that TGFβ(2) favours differentiation of asthmatic (myo)fibroblasts towards a smooth muscle phe...

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Detalhes bibliográficos
Main Authors: Wicks, J, Haitchi, H M, Holgate, S T, Davies, D E, Powell, R M
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2104615/
https://ncbi.nlm.nih.gov/pubmed/16449267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2005.050005
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