FLT3 mutations confer enhanced proliferation and survival properties to multipotent progenitors in a murine model of chronic myelomonocytic leukemia

SUMMARY: Despite their known transforming properties, the effects of leukemogenic FLT3-ITD mutations on hematopoietic stem and multipotent progenitor cells and on hematopoietic differentiation are not well understood. We report a mouse model harboring an ITD in the murine Flt3 locus that develops my...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Lee, Benjamin H., Tothova, Zuzana, Levine, Ross L., Anderson, Kristina, Buza-Vidas, Natalija, Cullen, Dana E., McDowell, Elizabeth P., Adelsperger, Jennifer, Fröhling, Stefan, Huntly, Brian J.P., Beran, Miloslav, Jacobsen, Sten Eirik, Gilliland, D. Gary
格式: Artigo
語言:Inglês
出版: 2007
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2104473/
https://ncbi.nlm.nih.gov/pubmed/17936561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2007.08.031
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍