טוען...
FLT3 mutations confer enhanced proliferation and survival properties to multipotent progenitors in a murine model of chronic myelomonocytic leukemia
SUMMARY: Despite their known transforming properties, the effects of leukemogenic FLT3-ITD mutations on hematopoietic stem and multipotent progenitor cells and on hematopoietic differentiation are not well understood. We report a mouse model harboring an ITD in the murine Flt3 locus that develops my...
שמור ב:
Main Authors: | , , , , , , , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
2007
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2104473/ https://ncbi.nlm.nih.gov/pubmed/17936561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2007.08.031 |
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