Stimulation of an α1-adrenergic receptor downregulates ecto-5′ nucleotidase activity on the apical membrane of RPE cells

The purines ATP and adenosine play an important role in the communication between the photoreceptors and the retinal pigment epithelium (RPE). While the RPE is known to release ATP into subretinal space, the source of extracellular adenosine is unclear. In other tissues, ecto-nucleotidases mediate t...

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Main Authors: Reigada, David, Zhang, Xiulan, Crespo, Ana, Nguyen, Johnathan, Liu, Ji, Pendrak, Klara, Stone, Richard A., Laties, Alan M., Mitchell, Claire
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2006
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2104005/
https://ncbi.nlm.nih.gov/pubmed/18404487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-005-3980-7
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