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Genetic and physiological relationships among the miaA gene, 2-methylthio-N6-(delta 2-isopentenyl)-adenosine tRNA modification, and spontaneous mutagenesis in Escherichia coli K-12.

The miaA tRNA modification gene was cloned and located by insertion mutagenesis and DNA sequence analysis. The miaA gene product, tRNA delta 2-isopentenylpyrophosphate (IPP) transferase, catalyzes the first step in the biosynthesis of 2-methylthio-N6-(delta 2-isopentenyl)-adenosine (ms2i6A) adjacent...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Principais autores: Connolly, D M, Winkler, M E
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1989
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC210042/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2656644/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.171.6.3233-3246.1989
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