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Genetic and physiological relationships among the miaA gene, 2-methylthio-N6-(delta 2-isopentenyl)-adenosine tRNA modification, and spontaneous mutagenesis in Escherichia coli K-12.

The miaA tRNA modification gene was cloned and located by insertion mutagenesis and DNA sequence analysis. The miaA gene product, tRNA delta 2-isopentenylpyrophosphate (IPP) transferase, catalyzes the first step in the biosynthesis of 2-methylthio-N6-(delta 2-isopentenyl)-adenosine (ms2i6A) adjacent...

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Bibliografische gegevens
Gepubliceerd in:J Bacteriol
Hoofdauteurs: Connolly, D M, Winkler, M E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 1989
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC210042/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2656644/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.171.6.3233-3246.1989
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