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Extrathymic Generation of Tumor-Specific T Cells from Genetically Engineered Human Hematopoietic Stem Cells via Notch Signaling

Adoptive cell transfer (ACT) of tumor-reactive lymphocytes has been shown to be an effective treatment for cancer patients. Studies in murine models of ACT indicated that antitumor efficacy of adoptively transferred T cells is dependent on the differentiation status of the cells, with lymphocyte dif...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhao, Yangbing, Parkhurst, Maria R., Zheng, Zhili, Cohen, Cyrille J., Riley, John P., Gattinoni, Luca, Restifo, Nicholas P., Rosenberg, Steven A., Morgan, Richard A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2100408/
https://ncbi.nlm.nih.gov/pubmed/17363559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-3977
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