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Evidence for a mediator cycle at the initiation of transcription

Free and elongating (DNA-bound) forms of RNA polymerase II were separated from yeast. Most cellular polymerase II was found in the elongating fraction, which contained all enzyme phosphorylated on the C-terminal domain and none of the 15-subunit mediator of transcriptional regulation. These and othe...

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Autores principales: Svejstrup, Jesper Q., Li, Yang, Fellows, Jane, Gnatt, Averell, Bjorklund, Stefan, Kornberg, Roger D.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences of the USA 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC21003/
https://ncbi.nlm.nih.gov/pubmed/9177171
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