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Accurate gene-tree reconstruction by learning gene- and species-specific substitution rates across multiple complete genomes

Comparative genomics provides a general methodology for discovering functional DNA elements and understanding their evolution. The availability of many related genomes enables more powerful analyses, but requires rigorous phylogenetic methods to resolve orthologous genes and regions. Here, we use 12...

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Bibliografiska uppgifter
Huvudupphovsmän: Rasmussen, Matthew D., Kellis, Manolis
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099600/
https://ncbi.nlm.nih.gov/pubmed/17989260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.7105007
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