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Accurate gene-tree reconstruction by learning gene- and species-specific substitution rates across multiple complete genomes

Comparative genomics provides a general methodology for discovering functional DNA elements and understanding their evolution. The availability of many related genomes enables more powerful analyses, but requires rigorous phylogenetic methods to resolve orthologous genes and regions. Here, we use 12...

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Detalhes bibliográficos
Main Authors: Rasmussen, Matthew D., Kellis, Manolis
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099600/
https://ncbi.nlm.nih.gov/pubmed/17989260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.7105007
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