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K-ras Mutations in Lung Tumors and Tumors from Other Organs are Consistent with a Common Mechanism of Ethylene Oxide Tumorigenesis in the B6C3F1 Mouse

Ethylene oxide is a multisite carcinogen in rodents and classified as a human carcinogen by the National Toxicology Program. In 2-year mouse studies, ethylene oxide (EO) induced lung, Harderian gland (HG), and uterine neoplasms. We evaluated representative EO-induced and equivalent spontaneous neopl...

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Detalhes bibliográficos
Main Authors: Hong, Hue-Hua L., Houle, Christopher D., Ton, Thai-Vu T., Sills, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099306/
https://ncbi.nlm.nih.gov/pubmed/17325976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01926230601063839
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