Spontaneous and UV-induced mutations in Escherichia coli K-12 strains with altered or absent DNA polymerase I.

The induction of mutations to valine resistance and to rifampin resistance occurs after UV irradiation in bacteria carrying a deletion through the polA gene (delta polA), showing that DNA polymerase I (PolI) is not an essential enzyme for this process. The PolI deletion strain showed a 7- to 10-fold...

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Pubblicato in:	J Bacteriol
Autori principali:	Bates, H, Randall, S K, Rayssiguier, C, Bridges, B A, Goodman, M F, Radman, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2651403/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.171.5.2480-2484.1989
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