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Spontaneous and UV-induced mutations in Escherichia coli K-12 strains with altered or absent DNA polymerase I.

The induction of mutations to valine resistance and to rifampin resistance occurs after UV irradiation in bacteria carrying a deletion through the polA gene (delta polA), showing that DNA polymerase I (PolI) is not an essential enzyme for this process. The PolI deletion strain showed a 7- to 10-fold...

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Udgivet i:J Bacteriol
Principais autores: Bates, H, Randall, S K, Rayssiguier, C, Bridges, B A, Goodman, M F, Radman, M
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209924/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2651403/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.171.5.2480-2484.1989
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