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Lacrimo-Auriculo-Dento-Digital Syndrome Is Caused by Reduced Activity of the Fibroblast Growth Factor 10 (FGF10)-FGF Receptor 2 Signaling Pathway

Lacrimo-auriculo-dento-digital (LADD) syndrome is characterized by abnormalities in lacrimal and salivary glands, in teeth, and in the distal limbs. Genetic studies have implicated heterozygous mutations in fibroblast growth factor 10 (FGF10) and in FGF receptor 2 (FGFR2) in LADD syndrome. However,...

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Bibliografische gegevens
Hoofdauteurs: Shams, Imad, Rohmann, Edyta, Eswarakumar, Veraragavan P., Lew, Erin D., Yuzawa, Satoru, Wollnik, Bernd, Schlessinger, Joseph, Lax, Irit
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099236/
https://ncbi.nlm.nih.gov/pubmed/17682060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00544-07
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