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Lacrimo-Auriculo-Dento-Digital Syndrome Is Caused by Reduced Activity of the Fibroblast Growth Factor 10 (FGF10)-FGF Receptor 2 Signaling Pathway

Lacrimo-auriculo-dento-digital (LADD) syndrome is characterized by abnormalities in lacrimal and salivary glands, in teeth, and in the distal limbs. Genetic studies have implicated heterozygous mutations in fibroblast growth factor 10 (FGF10) and in FGF receptor 2 (FGFR2) in LADD syndrome. However,...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shams, Imad, Rohmann, Edyta, Eswarakumar, Veraragavan P., Lew, Erin D., Yuzawa, Satoru, Wollnik, Bernd, Schlessinger, Joseph, Lax, Irit
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099236/
https://ncbi.nlm.nih.gov/pubmed/17682060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00544-07
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